Artificial intelligence (AI) has rapidly evolved from a futuristic concept to a transformative force driving industries across the globe. In recent years, AI startups have emerged at the forefront of innovation, solving complex problems and creating new opportunities in fields ranging from healthcare and finance to automation and customer service.
Since 2020, a wave of AI startups has secured impressive funding, ranging between $50 million to $100 million, fueling their growth and enabling them to develop cutting-edge technologies. These startups are not just following trends—they are shaping the future of AI and revolutionizing how businesses operate.
In this blog, we’ll spotlight 20 AI startups that have raised significant funding since 2020, highlighting their groundbreaking innovations and the industries they’re disrupting. Whether you’re an investor, entrepreneur, or simply an AI enthusiast, these companies are worth keeping an eye on as they continue to make their mark on the AI landscape.
Meet the 20 Startups That Raised $50M to $100M After 2020
The startup ecosystem has seen an impressive surge in funding over the past few years, with many innovative companies securing substantial investments to fuel their growth and expansion. These startups, spanning various industries, from tech and fintech to healthcare and sustainability, are paving the way for the future, solving complex problems, and driving meaningful change across the globe.
With funding rounds ranging from $50M to $100M, these companies are now poised to scale rapidly, enhance their offerings, and make a significant impact in their respective sectors. This level of investment signals strong market confidence and the immense potential these startups hold in reshaping industries.
Let’s dive into the world of these high-growth startups that have raised between $50M and $100M and are quickly emerging as leaders in their fields!
Company | Founded | Location | Employees | Last Funding | Last Funding Date | Total Funding |
---|---|---|---|---|---|---|
Decart | 2023 | San Francisco, CA, USA | 11-50 | $32M | Dec 19, 2024 | $56M |
You.com | 2020 | Palo Alto, CA, USA | 11-50 | $50M | Jun 17, 2024 | $95M |
Ambience Healthcare | 2020 | San Francisco, CA, USA | 11-50 | $70M | Feb 6, 2024 | $76.3M |
Hume AI | 2021 | New York, NY, USA | 11-50 | $50M | Mar 25, 2024 | $67.7M |
Regal | 2020 | New York, NY, USA | 101-250 | $40M | Oct 30, 2024 | $82.1M |
Galileo | 2021 | San Francisco, CA, USA | 51-100 | $45M | Oct 15, 2024 | $68.1M |
Ema | 2023 | Mountain View, CA, USA | 101-250 | $36M | Jul 31, 2024 | $61M |
Nooks | 2020 | San Francisco, CA, USA | 101-250 | $43M | Oct 22, 2024 | $70M |
SmarterDx | 2020 | New York, NY, USA | 101-250 | $50M | May 14, 2024 | $55.97M |
Harmonic | 2023 | Palo Alto, CA, USA | 11-50 | $75M | Sep 23, 2024 | $75M |
Decagon | 2023 | San Francisco, CA, USA | 11-50 | $65M | Oct 15, 2024 | $100M |
Mendaera | 2020 | San Mateo, CA, USA | 11-50 | $73M | Sep 26, 2024 | $97M |
Fireworks AI | 2022 | Redwood City, CA, USA | 11-50 | $52M | Jul 7, 2024 | $77M |
Unstructured Technologies | 2022 | Rocklin, CA, USA | 11-50 | $40M | Mar 14, 2024 | $65M |
Auger | 2024 | Bellevue, WA, USA | 1-10 | $100M | Oct 8, 2024 | $100M |
Contextual AI | 2023 | Mountain View, CA, USA | 1-10 | $80M | Aug 1, 2024 | $100M |
Captions | 2021 | New York, NY, USA | 11-50 | $60M | Jul 9, 2024 | $100M |
Tennr | 2021 | New York, NY, USA | 11-50 | $37M | Oct 22, 2024 | $60M |
Vectara | 2022 | Palo Alto, CA, USA | 11-50 | $25M | Jul 16, 2024 | $73.5M |
Yurts Technologies | 2022 | San Francisco, CA, USA | 11-50 | $40M | Dec 3, 2024 | $58.35M |
1. Decart
- Founded: 2023
- Location: San Francisco, California, USA
- Industry: Artificial Intelligence (AI), Generative AI, IT Infrastructure
- Number of Employees: 11-50
- Last Funding Amount: $32M (Latest Round: December 19, 2024)
- Total Funding Amount: $56M
Decart is an innovative AI platform focused on enhancing the training and inference processes of large generative models. The company’s advanced systems-level infrastructure aims to boost performance by tenfold, enabling more efficient development and deployment of complex AI models. Decart’s infrastructure platform is designed to solve key challenges in the AI field, including scalability and real-time interaction with generative models. By providing enhanced AI solutions, Decart seeks to drive advancements in multiple industries, helping businesses adopt generative AI technologies for more impactful applications.

2. You.com
- Founded: 2020
- Location: Palo Alto, California, USA
- Industry: Artificial Intelligence (AI), Chatbot, Generative AI
- Number of Employees: 11-50
- Last Funding Amount: $50M (Latest Round: June 17, 2024)
- Total Funding Amount: $95M
You.com is a groundbreaking AI-driven chatbot and search engine, developed by top AI research scientists. It leverages Large Language Models (LLM) to deliver human-like, personalized responses to user queries. The platform offers a suite of AI-powered tools—YouChat, YouCode, YouWrite, and YouImagine—that enhance web search, content creation, image generation, and code development.
By integrating advanced machine learning capabilities, You.com streamlines complex queries, supports research with up-to-date citations, and boosts productivity. Its ability to efficiently provide answers and assist with various tasks makes it a powerful tool for users seeking enhanced performance and time savings in their day-to-day work.

3. Ambience Healthcare
- Founded: 2020
- Location: San Francisco, California, USA
- Industry: Artificial Intelligence (AI), Health Care, Information Technology
- Number of Employees: 11-50
- Last Funding Amount: $70M (Latest Round: February 6, 2024)
- Total Funding Amount: $76.3M
Ambience Healthcare is revolutionizing the healthcare sector with its innovative generative AI technology. The company’s AI operating system offers a suite of applications designed to reduce clinician burnout, enhance system efficiency, and enable high-quality care. By using Ambience’s platform, healthcare systems have been able to reduce documentation time by an average of 78%, improve coding integrity, and achieve a return on investment of at least 5X. Through its advanced AI solutions, Ambience is empowering healthcare organizations to optimize operations, improve patient care, and significantly reduce administrative burdens, all while driving substantial cost savings.

4. Hume AI
- Founded: March 2021
- Location: New York, New York, USA
- Industry: Artificial Intelligence (AI), Information Technology, Machine Learning
- Number of Employees: 11-50
- Last Funding Amount: $50M (Latest Round: March 25, 2024)
- Total Funding Amount: $67.7M
Hume AI offers a science-backed toolkit for measuring, understanding, and improving the impact of technology on human emotion. With its advanced API, Hume enables businesses to analyze human expressive behavior across images, videos, audio, and text. This allows companies to build applications that can predict users’ intents, preferences, experiences, and outcomes more accurately. By utilizing Hume’s technology, developers and organizations can enhance user experiences and outcomes by better understanding and responding to human emotional signals. Founded in 2021, Hume AI is pioneering efforts to bridge the gap between technology and human emotion.

5. Regal
- Founded: 2020
- Location: New York, New York, USA
- Industry: Artificial Intelligence (AI), Enterprise Software, Marketing Automation
- Number of Employees: 101-250
- Last Funding Amount: $40M (Latest Round: October 30, 2024)
- Total Funding Amount: $82.1M
Regal offers AI-driven contact center software (CCaaS) that boosts sales, support, and customer retention. Their platform leverages AI conversation intelligence, processing 100% of interactions to provide insights and automation that increase conversion rates. Regal’s generative AI-powered tools are designed to assist agents and managers in improving customer interactions, helping businesses engage with clients more effectively and efficiently. Regal AI’s focus on automating personalization and optimizing communication allows organizations to scale and enhance their customer experience.

6. Galileo
- Founded: May 1, 2021
- Location: San Francisco, California, USA
- Industry: Artificial Intelligence (AI), Big Data, Developer Tools
- Number of Employees: 51-100
- Last Funding Amount: $45M (Latest Round: October 15, 2024)
- Total Funding Amount: $68.1M
Galileo is revolutionizing AI development by providing Evaluation Intelligence to help AI developers create trustworthy and efficient AI applications quickly. By offering an advanced platform for evaluating AI models, Galileo ensures that developers can easily test, monitor, and improve the accuracy and ethics of their AI systems. With a focus on speed and reliability, the platform allows for the fast deployment of AI tools while maintaining high standards of performance. Galileo empowers teams to tackle challenges in AI development, enabling them to produce better, more trustworthy AI applications.

7. Ema
- Founded: 2023
- Location: Mountain View, California, USA
- Industry: Artificial Intelligence (AI), Customer Service, Employee Benefits
- Number of Employees: 101-250
- Last Funding Amount: $36M (Latest Round: July 31, 2024)
- Total Funding Amount: $61M
Ema offers a Universal AI employee designed to automate complex workflows and improve productivity across organizations. Powered by its Generative Workflow Engine, Ema seamlessly integrates with enterprise applications, enabling users to delegate repetitive tasks efficiently. The platform leverages multiple AI models to ensure both accuracy and security, providing valuable automation solutions in business areas such as customer support, HR, and finance. By streamlining everyday tasks, Ema enhances operational efficiency and boosts employee productivity within organizations.

8. Nooks
- Founded: 2020
- Location: San Francisco, California, USA
- Industry: Artificial Intelligence (AI), Information Technology, Productivity Tools
- Number of Employees: 101-250
- Last Funding Amount: $43M (Latest Round: October 22, 2024)
- Total Funding Amount: $70M
Nooks is an AI dialing and prospecting company that develops a meeting and video communication platform designed to host engaging workshops, classes, and conferences. By automating manual call tasks and providing strategic insights, the platform helps increase sales productivity. Nooks further enhances the process by up-skilling sales representatives through AI-driven training and collaboration. Trusted by thousands of Sales Development Representatives (SDRs) and Account Executives (AEs), Nooks simplifies the workflow, eliminating busywork and boosting overall sales performance.

9. SmarterDx
- Founded: 2020
- Location: New York, New York, USA
- Industry: Artificial Intelligence (AI), Health Care, Hospital
- Number of Employees: 101-250
- Last Funding Amount: $50M (Latest Round: May 14, 2024)
- Total Funding Amount: $55.97M
SmarterDx develops an automated pre-bill review platform that helps hospitals maintain revenue integrity. The platform assists doctors in reviewing diagnosis charts, enabling them to make informed judgment calls, learn about new diagnoses, and educate other physicians. By automating the review process, SmarterDx ensures accuracy and efficiency in the healthcare billing process, reducing errors and improving revenue cycles for hospitals.

10. Harmonic
- Founded: 2023
- Location: Palo Alto, California, USA
- Industry: Artificial Intelligence (AI), EdTech, Software
- Number of Employees: 11-50
- Last Funding Amount: $75M (Latest Round: September 23, 2024)
- Total Funding Amount: $75M
Harmonic is pioneering the development of Mathematical Superintelligence (MSI), a next-generation artificial intelligence built on mathematical principles. This innovative AI technology ensures high accuracy and eliminates hallucinations, making it a powerful tool for solving complex mathematical problems. Harmonic’s mathematical reasoning engine is designed to tackle challenges that require advanced mathematical knowledge, setting a new standard for precision and reliability in AI.

11. Decagon
- Founded: 2023
- Location: San Francisco, California, USA
- Industry: Artificial Intelligence (AI), Generative AI, Software
- Number of Employees: 11-50
- Last Funding Amount: $65M (Latest Round: October 15, 2024)
- Total Funding Amount: $100M
Decagon offers AI-powered customer support agents designed for enterprises, helping them deliver exceptional customer experiences. Trusted by leading companies and startups, Decagon’s generative AI platform auto-resolves issues, streamlines workflows, and assists customer support agents while providing valuable insights. With seamless integrations tailored for success, Decagon helps businesses enhance their customer service capabilities and improve overall efficiency.

12. Mendaera
- Founded: 2020
- Location: San Mateo, California, USA
- Industry: Artificial Intelligence (AI), Health Care, Health Diagnostics
- Number of Employees: 11-50
- Last Funding Amount: $73M (Latest Round: September 26, 2024)
- Total Funding Amount: $97M
Mendaera is a medtech startup focused on developing advanced healthcare technologies, with an emphasis on robotics and diagnostic tools. The company aims to digitize clinical judgment and technical expertise to ensure high-quality care is accessible to all patients in every care facility. Mendaera’s platform integrates robotics, AI, real-time imaging, and connectivity, enabling medical interventions at scale. Currently in development, Mendaera’s solution is designed to enhance patient care by leveraging cutting-edge technology for greater efficiency and effectiveness in medical practices.

13. Fireworks AI
- Founded: October 2022
- Location: Redwood City, California, USA
- Industry: Artificial Intelligence (AI), Data Management, SaaS
- Number of Employees: 11-50
- Last Funding Amount: $52M (Latest Round: July 7, 2024)
- Total Funding Amount: $77M
Fireworks AI offers a generative AI platform as a service, optimized for rapid product iteration while minimizing cost to serve. The platform provides advanced tools for developing and deploying generative AI models, making it easier for businesses to integrate AI into their operations efficiently. Fireworks AI’s focus on affordability and speed enables companies to innovate quickly without compromising on quality.

14. Unstructured Technologies
- Founded: 2022
- Location: Rocklin, California, USA
- Industry: Artificial Intelligence (AI), Machine Learning, Natural Language Processing
- Number of Employees: 11-50
- Last Funding Amount: $40M (Latest Round: March 14, 2024)
- Total Funding Amount: $65M
Unstructured simplifies the process of converting raw data, such as PDFs and Microsoft Office documents, into formats ready for retrieval-augmented generation (RAG). Their platform continuously hydrates generative AI systems and supports integration with any third-party model thanks to its modular architecture. Unstructured supports over 25 file types and offers connectors to platforms like SharePoint, S3, and Databricks. By making data extraction and integration seamless, Unstructured helps businesses leverage their documents and maximize the value of their AI workflows.

15. Auger
- Founded: 2024
- Location: Bellevue, Washington, USA
- Industry: Artificial Intelligence (AI), Logistics, Machine Learning
- Number of Employees: 1-10
- Last Funding Amount: $100M (Latest Round: October 8, 2024)
- Total Funding Amount: $100M
Auger develops an AI-powered tool that integrates with existing inventory management systems to provide real-time insights for supply chain-dependent businesses. By leveraging advanced AI and machine learning, Auger pulls data from multiple sources to generate dynamic, automated insights. The platform offers a unified view across planning, forecasting, and financing, enabling teams to shift away from manual tasks and focus on driving innovation within their operations.

16. Contextual AI
- Founded: 2023
- Location: Mountain View, California, USA
- Industry: Artificial Intelligence (AI), Generative AI, Software
- Number of Employees: 1-10
- Last Funding Amount: $80M (Latest Round: August 1, 2024)
- Total Funding Amount: $100M
Contextual AI offers a pioneering approach to generative AI, specifically designed for the workplace. The company provides cutting-edge solutions that integrate generative AI into everyday business operations, streamlining workflows and enhancing productivity. By leveraging AI’s capabilities, Contextual AI enables organizations to harness data more efficiently and make informed decisions.
Their innovative approach helps businesses stay ahead of the competition by improving task automation and generating dynamic insights. Contextual AI is shaping the future of work, offering powerful tools to support companies in optimizing their processes and achieving greater success.

17. Captions
- Founded: 2021
- Location: New York, New York, USA
- Industry: Artificial Intelligence (AI), Content Creators, Generative AI
- Number of Employees: 11-50
- Last Funding Amount: $60M (Latest Round: July 9, 2024)
- Total Funding Amount: $100M
Captions is an AI-powered creative studio focused on developing a video creation and editing platform for content creators. The platform enhances video production by offering automatic subtitle generation, eye contact correction, language dubbing, and video clip extraction. These software solutions simplify the creative process, allowing creators to produce high-quality content efficiently. Captions is transforming the content creation landscape by using AI to streamline editing and ensure smoother video production for creators across industries.

18. Tennr
- Founded: 2021
- Location: New York, New York, USA
- Industry: Artificial Intelligence (AI), Health Care, Medical
- Number of Employees: 11-50
- Last Funding Amount: $37M (Latest Round: October 22, 2024)
- Total Funding Amount: $60M
Tennr is a healthcare AI startup focused on optimizing healthcare operations by automating back-office tasks. The company leverages AI technology to replace traditional faxing systems and streamline communication processes in healthcare, ensuring patients receive timely care. Tennr’s platform helps healthcare organizations improve efficiency by automating medical document management and simplifying communication, ultimately enhancing the overall patient experience and accelerating service delivery.

19. Vectara
- Founded: 2022
- Location: Palo Alto, California, USA
- Industry: Artificial Intelligence (AI), Developer Platform, Generative AI
- Number of Employees: 11-50
- Last Funding Amount: $25M (Latest Round: July 16, 2024)
- Total Funding Amount: $73.5M
Vectara offers a generative AI product platform for embedding AI features into applications. The company’s Serverless Retrieval Augmented Generation (RAG) API platform enables businesses to seamlessly integrate powerful generative AI functionality into their apps, chatbots, and products. It ensures results grounded in existing data, reducing hallucination, providing explainability, and enforcing access control. Vectara’s platform addresses critical issues for enterprise adoption, such as real-time updatability and mitigating IP and bias concerns, making it a trusted solution for integrating conversational AI and question-answering capabilities with precision.

20. Yurts Technologies
- Founded: July 1, 2022
- Location: San Francisco, California, USA
- Industry: Artificial Intelligence (AI), Software
- Number of Employees: 11-50
- Last Funding Amount: $40M (Latest Round: December 3, 2024)
- Total Funding Amount: $58.35M
Yurts is a generative AI platform designed for enterprise use. The company’s mission is to help individuals connect with their finest work by revolutionizing knowledge management and enterprise processes. Yurts combines Large Language Models (LLMs) with the practical power of generative AI applications, enabling businesses to engage with data more efficiently. Their platform provides GenAI-powered search and chat functionalities, making it a valuable tool for enterprise-scale knowledge management.

Conclusion
The AI landscape is evolving at an unprecedented pace, and these 20 startups are at the cutting edge of this transformation. With substantial funding ranging from $50 million to $100 million, these companies are positioned to scale their operations and bring their groundbreaking innovations to market. From revolutionizing healthcare and finance to enhancing customer service and automation, the impact of AI on industries across the globe is undeniable.
As they continue to grow, these startups are not only advancing the capabilities of artificial intelligence but also reshaping the future of work, business, and technology. With their ambitious goals and impressive backing, these companies are set to lead the way in AI innovation for years to come.
Whether you’re an investor, entrepreneur, or simply an AI enthusiast, keeping an eye on these startups is essential. Their groundbreaking work is not just pushing the boundaries of what’s possible—it’s laying the foundation for the future of artificial intelligence.
FAQs
Q. How do these AI companies impact everyday life?
Answer: These AI startups are revolutionizing everyday life by enhancing the way we interact with technology. From improving healthcare diagnoses to automating customer service interactions, their innovations make processes faster, more efficient, and more accessible to people around the world.
Q. What does the future hold for these AI startups?
Answer: With their significant funding and innovative technologies, these AI startups are well-positioned to scale and expand their reach. Over the next few years, they are likely to continue disrupting industries, advancing AI capabilities, and making a lasting impact on how businesses and consumers interact with AI-powered solutions.
Q. How can investors benefit from the growth of AI startups?
Answer: Investors can benefit by identifying high-growth AI startups that are poised to scale and disrupt industries. As these companies continue to innovate and expand, early investment in them could lead to significant returns, especially as AI becomes more integrated into businesses and everyday life. (DeFi).