The future of artificial intelligence is taking shape, and these 20 U.S.-based AI startups are leading the charge. Founded after 2015, they’ve secured $50M–$100M in funding to fuel groundbreaking innovations across industries like healthcare, finance, and logistics. Their advanced AI solutions are poised to transform how we work, live, and interact with technology.
Rising to the Top of the AI Revolution
With significant backing and cutting-edge technology, these startups are positioned to become the giants of tomorrow’s AI-driven world.
Let’s dive into the companies that are paving the way for the next era of artificial intelligence.
| Company | Founded | Location | Employees | Last Funding | Last Amount | Total Funding |
|---|---|---|---|---|---|---|
| EvolutionIQ | 2019 | New York, New York | 101–250 | Aug 14, 2024 | $20.15M | $63.45M |
| Imagry | 2015 | San Jose, California | 101–250 | Dec 19, 2024 | $3.5M | $59.46M |
| Finexio | 2015 | San Mateo, California | 101–250 | Dec 17, 2024 | $10M | $93.5M |
| Rad AI | 2018 | San Francisco, California | 51–100 | May 7, 2024 | $50M | $83M |
| Fundraise Up | 2017 | New York, New York | 251–500 | Jan 6, 2025 | $40M | $52.1M |
| Spot AI | 2018 | San Francisco, California | 101–250 | Oct 31, 2024 | $31M | $93M |
| Pearl | 2019 | West Hollywood, California | 101–250 | Jul 24, 2024 | $58M | $69M |
| Lily AI | 2015 | Mountain View, California | 101–250 | Mar 14, 2024 | $20M | $71.9M |
| Skyflow | 2019 | Palo Alto, California | 101–250 | Mar 28, 2024 | $27M | $97M |
| Clay | 2017 | New York, New York | 11–50 | Jun 27, 2024 | $46M | $62M |
| Brand Engagement Network | 2018 | Jackson, Wyoming | 51–100 | Aug 26, 2024 | $55.93M | $60.88M |
| Concentric AI | 2018 | San Jose, California | 51–100 | Oct 24, 2024 | $45M | $67M |
| Eve | 2016 | San Francisco, California | 11–50 | Jan 16, 2025 | $47M | $61M |
| VERSES | 2018 | Los Angeles, California | 101–250 | Jan 7, 2025 | CA$20M | $61.81M |
| Vanilla | 2019 | Salt Lake City, Utah | 101–250 | Aug 15, 2024 | $35M | $81.4M |
| DreamBig Semiconductor | 2019 | San Jose, California | 101–250 | Jul 16, 2024 | $75M | $92.5M |
| Opkey | 2015 | Dublin, California | 251–500 | Aug 22, 2024 | $47M | $57M |
| Censia | 2017 | San Francisco, California | 101–250 | Sep 18, 2024 | $38M | $66.63M |
| Baseten | 2019 | San Francisco, California | 11–50 | Mar 4, 2024 | $40M | $60M |
| Pieces | 2015 | Irving, Texas | 101–250 | Sep 10, 2024 | $25M | $86.48M |
1. EvolutionIQ
- Founded: Jan 1, 2019
- Location: New York, New York
- Industry: Artificial Intelligence (AI), Commercial Insurance
- Number of Employees: 101-250
- Last Funding Amount: $20.15M (Latest Round: Aug 14, 2024)
- Total Funding Amount: $63.45M
EvolutionIQ is an innovative company that leverages artificial intelligence (AI) to transform the commercial insurance industry. Founded in January 2019 and headquartered in New York, the company uses AI-powered solutions to optimize claims processing and underwriting. With a growing team of 101-250 employees, EvolutionIQ has secured significant funding, including a recent $20.15M round in August 2024.
2. Imagry
- Founded: 2015
- Location: San Jose, California
- Industry: Artificial Intelligence (AI), Automotive
- Number of Employees: 101-250
- Last Funding Amount: $3.5M (Latest Round: Dec 19, 2024)
- Total Funding Amount: $59.46M
Imagry is a pioneering company specializing in artificial intelligence (AI) for the automotive industry. Founded in 2015 and based in San Jose, California, Imagry focuses on creating advanced AI systems that enhance autonomous driving technology. With a team of 101-250 employees, the company has raised substantial funding, including a recent $3.5M round in December 2024.
3. Finexio
- Founded: 2015
- Location: San Mateo, California
- Industry: Artificial Intelligence (AI), B2B
- Number of Employees: 101-250
- Last Funding Amount: $10M (Latest Round: Dec 17, 2024)
- Total Funding Amount: $93.5M
Finexio is a leading B2B company that uses artificial intelligence (AI) to transform payment processes in business transactions. Founded in 2015 and headquartered in San Mateo, California, Finexio offers innovative AI-driven solutions to streamline accounts payable systems. The company has raised a total of $93.5M in funding, including a recent $10M round in December 2024.
4. Rad AI
- Founded: 2018
- Location: San Francisco, California
- Industry: Artificial Intelligence (AI), Enterprise Software
- Number of Employees: 51-100
- Last Funding Amount: $50M (Latest Round: May 7, 2024)
- Total Funding Amount: $83M
Rad AI is an enterprise software company that utilizes artificial intelligence (AI) to optimize workflows in the healthcare industry. Founded in 2018 and based in San Francisco, California, Rad AI is focused on developing AI-powered solutions that enhance radiology and medical imaging processes. With a team of 51-100 employees, the company has secured $83M in total funding, including a recent $50M round in May 2024.
5. Fundraise Up
- Founded: Nov 14, 2017
- Location: New York, New York
- Industry: Artificial Intelligence (AI), B2B
- Number of Employees: 251-500
- Last Funding Amount: $40M (Latest Round: Jan 6, 2025)
- Total Funding Amount: $52.1M
Fundraise Up is a B2B company using artificial intelligence (AI) to optimize fundraising for nonprofits. Founded on November 14, 2017, and based in New York, the company provides innovative solutions that help organizations increase donations through AI-driven tools. With a growing team of 251-500 employees, Fundraise Up has raised a total of $52.1M in funding, including a recent $40M round in January 2025.
6. Spot AI
- Founded: Feb 7, 2018
- Location: San Francisco, California
- Industry: Artificial Intelligence (AI), Enterprise Software
- Number of Employees: 101-250
- Last Funding Amount: $31M (Latest Round: Oct 31, 2024)
- Total Funding Amount: $93M
Spot AI is a leading enterprise software company that specializes in artificial intelligence (AI) solutions for video surveillance and analytics. Founded on February 7, 2018, and headquartered in San Francisco, California, Spot AI provides AI-driven tools to enhance security and business intelligence. With a team of 101-250 employees, the company has raised a total of $93M in funding, including a recent $31M round in October 2024.
7. Pearl
- Founded: Apr 30, 2019
- Location: West Hollywood, California
- Industry: Artificial Intelligence (AI), Dental
- Number of Employees: 101-250
- Last Funding Amount: $58M (Latest Round: Jul 24, 2024)
- Total Funding Amount: $69M
Pearl is an innovative AI-driven company focused on transforming the dental industry. Founded on April 30, 2019, and based in West Hollywood, California, Pearl uses artificial intelligence to enhance diagnostic and clinical workflows for dental practices. With a team of 101-250 employees, the company has raised a total of $69M in funding, including a recent $58M round in July 2024.
8. Lily AI
- Founded: Feb 2015
- Location: Mountain View, California
- Industry: Artificial Intelligence (AI), E-Commerce
- Number of Employees: 101-250
- Last Funding Amount: $20M (Latest Round: Mar 14, 2024)
- Total Funding Amount: $71.9M
Lily AI is a cutting-edge AI company focused on enhancing the e-commerce industry. Founded in February 2015 and based in Mountain View, California, Lily AI specializes in using artificial intelligence to personalize shopping experiences and optimize product discovery. With a team of 101-250 employees, the company has raised a total of $71.9M in funding, including a recent $20M round in March 2024.
9. Skyflow
- Founded: Mar 15, 2019
- Location: Palo Alto, California
- Industry: Artificial Intelligence (AI), Cyber Security
- Number of Employees: 101-250
- Last Funding Amount: $27M (Latest Round: Mar 28, 2024)
- Total Funding Amount: $97M
Skyflow is an innovative AI-driven company focused on enhancing cybersecurity. Founded on March 15, 2019, and based in Palo Alto, California, Skyflow offers privacy-preserving data infrastructure that helps organizations protect sensitive data using artificial intelligence. With a team of 101-250 employees, the company has raised a total of $97M in funding, including a recent $27M round in March 2024.
10. Clay
- Founded: Jul 25, 2017
- Location: New York, New York
- Industry: Artificial Intelligence (AI), Developer Tools
- Number of Employees: 11-50
- Last Funding Amount: $46M (Latest Round: Jun 27, 2024)
- Total Funding Amount: $62M
Clay is an AI-driven company focused on providing developer tools to streamline software development. Founded on July 25, 2017, and based in New York, Clay offers innovative solutions designed to enhance the productivity and efficiency of developers. With a team of 11-50 employees, the company has raised a total of $62M in funding, including a recent $46M round in June 2024.
11. Brand Engagement Network
- Founded: 2018
- Location: Jackson, Wyoming
- Industry: Artificial Intelligence (AI), Information Technology
- Number of Employees: 51-100
- Last Funding Amount: $55.93M (Latest Round: Aug 26, 2024)
- Total Funding Amount: $60.88M
Brand Engagement Network is an AI-driven company specializing in the information technology sector. Founded in 2018 and located in Jackson, Wyoming, the company focuses on using artificial intelligence to help businesses improve brand engagement and customer interactions. With a team of 51-100 employees, Brand Engagement Network has raised a total of $60.88M in funding, including a recent $55.93M round in August 2024.
12. Concentric AI
- Founded: Nov 2018
- Location: San Jose, California
- Industry: Artificial Intelligence (AI), Network Security
- Number of Employees: 51-100
- Last Funding Amount: $45M (Latest Round: Oct 24, 2024)
- Total Funding Amount: $67M
Concentric AI is a leading AI-driven company focused on enhancing network security. Founded in November 2018 and based in San Jose, California, Concentric AI uses artificial intelligence to provide advanced solutions for securing and managing sensitive data across networks. With a team of 51-100 employees, the company has raised a total of $67M in funding, including a recent $45M round in October 2024.
13. Eve
- Founded: 2016
- Location: San Francisco, California
- Industry: Artificial Intelligence (AI), Information Technology
- Number of Employees: 11-50
- Last Funding Amount: $47M (Latest Round: Jan 16, 2025)
- Total Funding Amount: $61M
Eve is an AI-driven company focused on the information technology sector. Founded in 2016 and based in San Francisco, California, Eve specializes in providing artificial intelligence solutions to streamline IT operations and enhance business efficiency. With a team of 11-50 employees, the company has raised a total of $61M in funding, including a recent $47M round in January 2025.
14. VERSES
- Founded: Sep 19, 2018
- Location: Los Angeles, California
- Industry: Artificial Intelligence (AI), Intelligent Systems
- Number of Employees: 101-250
- Last Funding Amount: CA$20M (Latest Round: Jan 7, 2025)
- Total Funding Amount: $61.81M
VERSES is an innovative AI company specializing in intelligent systems. Founded on September 19, 2018, and based in Los Angeles, California, VERSES leverages artificial intelligence to build advanced systems for various industries. With a team of 101-250 employees, the company has raised a total of $61.81M in funding, including a recent CA$ 20M round in January 2025.
15. Vanilla
- Founded: 2019
- Location: Salt Lake City, Utah
- Industry: Artificial Intelligence (AI), Financial Services
- Number of Employees: 101-250
- Last Funding Amount: $35M (Latest Round: Aug 15, 2024)
- Total Funding Amount: $81.4M
Vanilla is an AI-driven company specializing in financial services. Founded in 2019 and located in Salt Lake City, Utah, Vanilla uses artificial intelligence to provide innovative solutions that enhance financial operations and services. With a team of 101-250 employees, the company has raised a total of $81.4M in funding, including a recent $35M round in August 2024.
16. DreamBig Semiconductor
- Founded: Oct 2019
- Location: San Jose, California
- Industry: Artificial Intelligence (AI), Data Center
- Number of Employees: 101-250
- Last Funding Amount: $75M (Latest Round: Jul 16, 2024)
- Total Funding Amount: $92.5M
DreamBig Semiconductor is an AI-driven company specializing in data center solutions. Founded in October 2019 and based in San Jose, California, DreamBig Semiconductor focuses on developing cutting-edge semiconductor technologies powered by artificial intelligence to optimize data center operations. With a team of 101-250 employees, the company has raised a total of $92.5M in funding, including a recent $75M round in July 2024.
17. Opkey
- Founded: 2015
- Location: Dublin, California
- Industry: Artificial Intelligence (AI), Penetration Testing
- Number of Employees: 251-500
- Last Funding Amount: $47M (Latest Round: Aug 22, 2024)
- Total Funding Amount: $57M
Opkey is a leading AI-driven company specializing in penetration testing for cybersecurity. Founded in 2015 and based in Dublin, California, Opkey focuses on providing automated security testing solutions powered by artificial intelligence to help businesses identify vulnerabilities. With a team of 251-500 employees, the company has raised a total of $57M in funding, including a recent $47M round in August 2024.
18. Censia
- Founded: 2017
- Location: San Francisco, California
- Industry: Artificial Intelligence (AI), Employment
- Number of Employees: 101-250
- Last Funding Amount: $38M (Latest Round: Sep 18, 2024)
- Total Funding Amount: $66.63M
Censia is an AI-driven company specializing in employment solutions. Founded in 2017 and based in San Francisco, California, Censia uses artificial intelligence to optimize talent acquisition and workforce management processes for businesses. With a team of 101-250 employees, the company has raised a total of $66.63M in funding, including a recent $38M round in September 2024.
19. Baseten
- Founded: 2019
- Location: San Francisco, California
- Industry: Artificial Intelligence (AI), Developer Tools
- Number of Employees: 11-50
- Last Funding Amount: $40M (Latest Round: Mar 4, 2024)
- Total Funding Amount: $60M
Baseten is an AI-driven company specializing in developer tools. Founded in 2019 and located in San Francisco, California, Baseten provides tools that help developers build, deploy, and manage AI-powered applications quickly and efficiently. With a team of 11-50 employees, the company has raised a total of $60M in funding, including a recent $40M round in March 2024.
20. Pieces
- Founded: 2015
- Location: Irving, Texas
- Industry: Artificial Intelligence (AI), Enterprise Software
- Number of Employees: 101-250
- Last Funding Amount: $25M (Latest Round: Sep 10, 2024)
- Total Funding Amount: $86.48M
Pieces is an AI-driven company specializing in enterprise software solutions. Founded in 2015 and based in Irving, Texas, Pieces uses artificial intelligence to streamline business processes and enhance decision-making in large organizations. With a team of 101-250 employees, the company has raised a total of $86.48M in funding, including a recent $25M round in September 2024.
Conclusion
These 20 U.S.-based AI startups, each backed by $50M–$100M, are at the forefront of transforming industries with intelligent, scalable solutions. From precision healthcare and automated finance to smart logistics and data-driven decision-making, they’re turning advanced AI into real-world impact. As they scale, these companies are defining what the next phase of the AI revolution looks like—bold, intelligent, and deeply integrated into everyday life.
FAQs
Q1. Why are these AI startups raising $50M–$100M?
A. This level of funding supports aggressive scaling, product refinement, global expansion, and deeper R&D to maintain technological leadership.
Q2. What industries are most impacted by their innovations?
A. Healthcare, finance, logistics, cybersecurity, and enterprise software are key areas seeing transformation from these startups.
Q3. What’s driving their rapid growth?
A. Strong product-market fit, demand for intelligent automation, and the need for industry-specific AI tools that go beyond generic platforms.